"A meta-analysis of 37 studies and over 9,000 participants, published in the BMJ, which found that people who stop taking weight-loss medications regain weight at roughly four times the rate of people coming off behavioral programs, with the average person returning to their baseline weight within 1.7 years."
"Some plan to be on the meds forever. Others have been off for months and are quietly thriving. A few are somewhere in the messy middle."
"The answers were surprisingly candid about not only regaining weight but also about the relentless mental chatter known as “food noise,” the shock of experiencing fullness for the first time, the side effects no one warned them about, and the practical strategies people are using to make their results stick."
"“I skipped a dose one week by accident and craved hot dogs something fierce. That Costco hot dog hit the spot.”"
GLP-1 medications such as Ozempic, Wegovy, Mounjaro, and Zepbound became widely popular for enabling weight loss. A meta-analysis of 37 studies with over 9,000 participants found that people who stop these medications regain weight at about four times the rate of people who stop behavioral programs. The average person returned to baseline weight within about 1.7 years. Responses from online communities described weight regain after stopping, increased cravings, and persistent “food noise.” Some people reported unexpected experiences with fullness and side effects. Others shared strategies to maintain results, including dietary planning and continued behavior changes, while some planned to stay on medication long term.
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