"According to 50 Top Pizza, America's second-best pizzeria is Pizzeria Sei - the same pizzeria that tops Tasting Table's ranking of the 20 absolute best pizza places in Los Angeles. Pizzeria Sei prides itself on its intimate atmosphere and concise menu. It only offers eight different, Neapolitan-style pizzas. Not only is it recognized as one of the best in the U.S., but 50 Top Pizza also crowned it as the ninth-best pizzeria in the world in 2025."
"Following Pizzeria Sei as the third best pizza place in the U.S. is Tony's Pizza Napoletana in San Francisco. The restaurant operates with a full bar, seven ovens, and a very expansive menu that offers pizzas baked in 12 different styles - including the regionally popular California-style pizza. All made with ingredients largely sourced from Italy, Tony's Pizza Napoletana also ranks as the 10th best pizzeria in the world in 2025."
"According to 50 Top Pizza, the best pizza in the U.S. is still made on the Lower East Side of Manhattan, at a restaurant called Una Pizza Napoletana. The restaurant also held the title as the best pizza in the world in 2024 and 2022, and tied with I Masanielli in Caserta, Italy as the best pizza worldwide in 2025. Despite its popularity, the pizzeria only has one location, keeping its operations on a small scale."
50 Top Pizza's 2025 ranking places Una Pizza Napoletana on Manhattan's Lower East Side as the best pizza in the U.S., tying for the world top spot in 2025 and previously holding world titles in 2024 and 2022. Pizzeria Sei in Los Angeles ranks second nationally and ninth globally, offering an intimate atmosphere and a concise menu of eight Neapolitan-style pizzas. Tony's Pizza Napoletana in San Francisco ranks third nationally and tenth globally, operating with a full bar, seven ovens, and an expansive menu featuring pizzas baked in 12 different styles using ingredients largely sourced from Italy.
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