"The CDC published a study in the MMWR last month examining this year's flu shot effectiveness with the same design. The method gained a higher profile during the pandemic, with hundreds of studies using it to estimate COVID-19 vaccine effectiveness."
"Nixon said Bhattacharya was concerned by the observational method used in the study to calculate vaccine effectiveness and wants to make sure that the paper uses the most appropriate methodology for such a study."
"Dan Jernigan suggested that stalling the paper fits with Kennedy's anti-vaccine agenda, stating that if you're putting out an MMWR that the vaccine is effective at preventing hospitalizations, that message is not in line with the direction you've been taking."
Test-negative case-control design studies are commonly used to evaluate vaccine effectiveness, including flu shots and COVID-19 vaccines. The CDC has utilized this method, which gained prominence during the pandemic. While potential biases exist, the method is generally reliable when controlled. Concerns have been raised regarding the methodology of a specific study, prompting a review by CDC leadership. Critics suggest that delaying publication aligns with anti-vaccine agendas, particularly in light of recent political actions against vaccine availability.
Read at Ars Technica
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