"The research suggested that people drinking the equivalent of about two cups of coffee daily have 60% lower odds of developing osteoporosis than people who drink little or no caffeine. The protective effect of caffeine kicked in at around 107 milligrams of caffeine per day, roughly equivalent to one strong cup of coffee or two cups of tea. People consuming more than 168 milligrams daily - about two cups of coffee - showed the strongest protection against bone loss."
"To determine whether caffeine actually causes better bone health - rather than just being associated with it - the researchers employed a Mendelian Randomization (MR) method, which accounts for genetic variations. The study found that people who were genetically predisposed to drink more coffee had lower osteoporosis rates. Importantly, the reverse wasn't true - having osteoporosis didn't influence coffee drinking habits - suggesting caffeine intake genuinely helps protect bones."
Analysis of NHANES data from 2,863 adults linked moderate caffeine intake to substantially lower osteoporosis risk. Protective effects began near 107 milligrams of caffeine per day, about one strong cup of coffee or two cups of tea, with the greatest benefit observed above 168 milligrams per day—approximately two cups of coffee—after which benefits leveled off in an L-shaped pattern. A Mendelian Randomization approach accounting for genetic variation indicated genetic predisposition to higher coffee consumption associated with lower osteoporosis rates, while genetic predisposition to osteoporosis did not predict coffee intake. Caffeine is recognized for central nervous, cardiovascular, neuroendocrine benefits and has emerging orthopedic relevance.
Read at Daily Coffee News by Roast Magazine
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