The Boston Red Sox host the Minnesota Twins at Fenway Park on Friday, May 22, 2026, with an opening pitch scheduled for 7:10 p.m. ET. The game is available live on NESN and Twins.TV, with a live stream option through Fubo. Boston enters with a 22-27 record and will start Payton Tolle, who is 2-2 with a 2.05 ERA and 30 strikeouts over 30 2/3 innings. Minnesota enters at 23-27 and will start Connor Prielipp. Boston has won 15 of 31 moneyline games, while Minnesota has won 16 of 34 games as underdogs. Boston’s team ERA is 3.68 and its WHIP is 1.228, while Minnesota’s team ERA is 4.20 and its WHIP is 1.317.
"The Boston Red Sox (22-27), with Payton Tolle on the mound, host the Minnesota Twins (23-27) who will start Connor Prielipp, at 7:10 p.m. ET on Friday. If you're intending to watch this game, keep reading for streaming and TV options for the Boston-Minnesota matchup. When is Red Sox vs. Twins and when does it start? This contest between the Red Sox and Twins is on Friday, May 22, 2026. Expect to see the opening pitch at 7:10 p.m. ET."
"Where to watch Red Sox vs. Twins The Red Sox and Twins will hit the diamond at Fenway Park for this matchup on May 22, and if you would like to see the event live, get your tickets now from Vivid Seats! What channel is the game on? You can catch this game live on NESN and Twins.TV. Watch the Red Sox vs. Twins live stream on Fubo Live Stream Online: Sign up for Fubo today!"
"Red Sox Stats, Odds & Insights The Red Sox have won 15 of the 31 games they were the moneyline favorite this season (48.4%). Boston has hit the second-fewest home runs in MLB play this season (36). The Red Sox are slugging .366, the fourth-lowest average in baseball. Boston's 3.68 team ERA ranks ninth across all MLB pitching staffs. Pitchers for the Red Sox combine for the No. 9-ranked WHIP in baseball (1.228)."
"Twins Stats, Odds & Insights The Twins have won 16, or 47.1%, of the 34 games they've played as underdogs this season. Minnesota ranks 13th in Major League Baseball with 55 home runs. The Twins rank 15th in the majors with a .387 team slugging percentage. Minnesota pitchers have a combined ERA of 4.20 ERA this year, which ranks 17th in MLB. Twins pitchers have a 1.317 WHIP this season, 18th in the majors."
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