What is the science behind 'science-backed' supplements?

"A systematic review of 22 trials showed that the herb significantly improved stress, depression and anxiety. However, the authors also noted that the studies were generally low in quality and varied in what they measured, stating that ashwagandha should not yet be regarded as a definitive treatment option but rather as a promising complementary strategy that warrants further investigation."

"In the past few years, ashwagandha supplements have exploded in popularity, with worldwide use estimated to have quadrupled since 2020. In keeping with its traditional use, the plant is best known for its ability to calm and soothe. However, social-media platforms are awash with posts saying that the root not only reduces stress and improves sleep, but also boosts energy and testosterone levels, supports cognitive health and lowers inflammation."

"Ashwagandha's new-found fame has also drawn the attention of regulators. The French Agency for Food, Environmental and Occupational Health and Safety issued a warning advising against its use by pregnant people, children and individuals with various medical conditions. The UK Food Standards Agency is also reviewing its safety. Supplements containing the compound were banned in Denmark in 2023."

Ashwagandha, derived from Withania somnifera roots, has been used in Ayurvedic medicine for over two thousand years as a resilience-building tonic. Supplement use has quadrupled since 2020, with marketing claims extending beyond traditional stress-relief to include energy, testosterone, cognitive health, and inflammation reduction. A systematic review of 22 trials confirmed benefits for stress, depression, and anxiety, but researchers noted low study quality and measurement inconsistencies, recommending ashwagandha as a complementary strategy rather than definitive treatment. Regulatory bodies including French and UK agencies have raised safety concerns, particularly for pregnant individuals and children, while Denmark banned ashwagandha supplements in 2023.

Read at Nature