A revolutionary treatment for type 1 diabetes using a stem cell infusion called Zimislecel has shown promising results. Out of 12 patients treated, 10 no longer require insulin, and the other two need significantly lower doses. The therapy involves reprogramming stem cells into pancreatic islet cells, which are injected and implanted in the liver, where they produce insulin. This notable breakthrough could lead to a functional cure for type 1 diabetes, especially benefiting those with hypoglycemic unawareness, who cannot detect blood sugar fluctuations effectively.
This study represents for the first time that biologic replacement can be administered to patients with type 1 diabetes in a single safe and effective procedure with minimal risk to the recipient.
The groundbreaking therapy's foundation uses stem cells that researchers manipulated to become pancreatic islet cells, tiny clusters of specialized cells scattered throughout the pancreas that produce hormones to regulate blood sugar.
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