A recent Norwegian study highlights alarming side effects of Janus kinase inhibitors (JAKs), often used for autoimmune diseases. While these medications help manage conditions like rheumatoid arthritis, they may also facilitate the spread of various viruses, including influenza A and SARS-CoV-2. Researchers found that JAKs suppress essential interferon-stimulated genes, weakening the body’s defense against infections. This finding has raised concerns about prescribing these drugs to at-risk patients, emphasizing the need for further research to ensure they are used safely, particularly during viral outbreaks or pandemics.
"We have found a surprising and potentially serious side effect of a class of anti-inflammatory drugs. They can help viruses spread more easily in the body."
"Among the viruses that more easily affect the body with the help of these drugs are Rift Valley fever virus, influenza A, adenovirus and SARS-CoV-2, the virus that causes COVID-19."
"We recommend further studies to better understand how the drugs can be used optimally, especially during virus outbreaks or pandemics."
Collection
[
|
...
]