#cyclin-a
#cyclin-a

[ follow ]

#small-cell-lung-cancer #rb1 #tp53 #e2f1

Targeting G1-S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors - Nature

Disrupting the cyclin A–E2F1 interaction selectively induces apoptosis in RB1/TP53-deficient small cell lung cancer, offering a synthetic lethal therapeutic strategy.

[ Load more ]

#cyclin-a#cyclin-a

Targeting G1-S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors - Nature

#cyclin-a
#cyclin-a