He invented a successful medical device as a student. Here's his advice for new grads
Briefly

This would be able to be put into patients without the need for a major operation. Normally, of course, you would have to split the sternum.
Doctors insert the Impella through an artery in the patient's leg and guide it up to the heart's pumping chamber, using a tiny turbine to assist with blood circulation gently.
Siess remembers the nervousness of treating the first human patient with the Impella in 1999, who has since not encountered further heart problems.
Siess advises aspiring inventors to persevere through initial failures, as success often requires years of dedication, vision-sharing, and regulatory approval processes.
Read at www.npr.org
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