Scientists discovered a DNA 'gene desert' linked to IBD in white blood cells, causing overactive cytokine release and intestinal inflammation.
This genetic weak spot acts as a 'master regulator' of macrophage function, dictating chemical release and playing a central role in IBD.
The 'gene desert' appears only in individuals with IBD, leading to an abnormal immune response and potentially life-threatening consequences if left untreated.
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