Infinite Accumulation is Japanese artist Yayoi Kusama's first permanent public artwork in the UK and her largest permanent public sculpture.
The spheres symbolize unique personalities while the supporting curvilinear lines allow us to imagine an underpinning social structure.
TfL called it a 'monumental addition', while Justine Simons, deputy mayor for culture and the creative industries, said 'commuters and visitors are in for a real treat'.
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