"About to start vaccine and therapeutic clinical trials to protect high-risk groups," Butera said on X, without giving details of the drug to be tested.
The disease, which has symptoms from severe headache to vomiting, muscle and stomach ache, was first confirmed late in September.
According to Rwandan Health Ministry data, 36 cases of the illness, which has a fatality rate as high as 88%, have been reported so far.
The ministry was monitoring 410 people who had made contact with those infected, he added, while five more had now tested negative.
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