Nick Lodolo struck out 10 in 5 2/3 innings in his first big league start in almost a year, allowing just one hit and one walk.
Cincinnati's manager David Bell praised Lodolo's performance, highlighting the hard work that paid off in a stellar first outing.
White Sox manager Pedro Grifol acknowledged the strong pitching but expressed disappointment in the team's offensive performance.
A frustrated crowd at Guaranteed Rate Field directed chants at owner Jerry Reinsdorf, reflecting the White Sox's rough start with minimal runs scored.
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