Bernardino entered with a 4-3 lead and two on in relief of Bello (6-2) and promptly walked pinch hitter Ryan Mountcastle, loading the bases. But he struck out pinch-hitter Austin Hayes, induced a weak grounder from Jorge Mateo back to the mound for a force out and then struck out Gunnar Henderson on three pitches to end the threat.
Boston added three runs in the eighth on pinch-hitter Romy Gonzalez's sacrifice fly and Refsnyder's two-run homer.
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