Arsenal dominated possession and encountered stiff resistance in the first half from Burnley but they took the lead on the stroke of halftime when Leandro Trossard headed home before clattering into the post.
Burnley equalised nine minutes into the second half when Josh Brownhill scored with a deflected effort but centre back William Saliba restored Arsenal's lead two minutes later from a corner.
Arsenal's night afternoon on a sour note when Fabio Vieira was sent off for a high boot when he caught Brownhill on the knee with a mistimed challenge.
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