Cancer
fromNature
4 weeks agoAntibodies unleashed against pancreatic cancer
An antibody that blocks pancreatic cancer immune-evasion slows tumour growth and could provide a new treatment approach for pancreatic ductal adenocarcinoma.
In a medical first, researchers report that they have implanted CRISPR-edited pancreas cells into a person with type 1 diabetes. The cells pumped out sugar-regulating insulin for months - without the need for the recipient to take immune-dampening drugs, thanks to gene edits that allowed the cells, collected from a deceased donor, to evade detection by the recipient's immune system.