#epigenetics

#epigenetics

For decades, medicine has been dominated by a "fix-it-when-it-breaks" mentality. We wait for disease to appear, then react. But when the machinery in question is the only body you'll ever have, waiting until failure is both risky and costly. A better way forward, what I call healthspan medicine, is proactive, preventive, and personal. The Intersection of Psychology and Biology Healthspan medicine blends advances in diagnostics, geroscience, systems biology, and artificial intelligence with a clear-eyed recognition that our biology is deeply influenced by our psychology.

A huge analysis of epigenetic changes throughout the entire adult lifespan provides the most comprehensive picture to date of how ageing modifies our genes. The study reveals that some human tissues, such as the retina and stomach, accumulate more ageing-related DNA changes than do others, such as the cervix and skin, and found universal epigenetic markers of ageing across different organs.

Calculating biological age is core to the advancements in the science of aging, providing insight into the pace of an individual's aging process and potential health risks.

What they're showing is extremely convincing; I would say that it's a landmark in the field, highlighting how environmental pressures induce heritable changes without affecting DNA.