#cancer-drug-development

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#cereblon-protein #targeted-protein-degradation #allosteric-binding-sites #drug-selectivity-and-safety
Cancer
fromHarvard Gazette
4 days ago

Unlocking hidden pocket on a billiondollar drug target - Harvard Gazette

Researchers discovered a hidden binding pocket on cereblon protein that enables more selective and safer cancer drug design through targeted protein degradation.
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