Well barring a last minute blockbuster trade, it really seems like the Opening Day rotation will look like Chris Sale, Spencer Strider, Reynaldo Lopez, Grant Holmes, and the winner of the competition between Bryce Elder, Joey Wentz, and perhaps some other options, if they can all make it there healthy. You will note that Sale has had an extensive injury history, Strider is still looking to fully recover from his UCL internal brace surgery,
The FanGraphs Depth Chart assignment has Elder throwing 109 innings as a starter and ten in relief; for Wentz, it's 18 innings as a starter and 34 in relief. The range of other projection systems features the combination of these two guys going about 110 to 240 innings, though you shouldn't take the upper end of that range seriously because that's more of a "how healthy are they?" measure than a depth chart-informed one.