"Chen report the discovery of microorganisms that use energy derived from sulfide oxidation and iron-oxide reduction to drive carbon fixation (S.-C. Chen et al. Nature https://doi.org/g9zqq2; 2025)."
"In our view, these microbes (known as MISO organisms) could be used for sustainable biotechnology."
Microorganisms have been identified that couple sulfide oxidation to iron-oxide reduction to drive autotrophic carbon fixation. These MISO organisms perform chemolithotrophic metabolism, deriving energy from inorganic sulfide and iron redox reactions to assimilate CO2. Metabolic coupling of sulfide oxidation and iron reduction enables survival and growth in anoxic, sulfidic environments with abundant iron minerals. Potential applications include carbon capture, bioremediation of sulfide- and iron-impacted sites, and bioenergy production by exploiting natural redox gradients and mineral electron acceptors. Isolation, metabolic characterization, and scalable cultivation strategies will be needed to realize practical biotechnological uses.
#sulfide-oxidation #iron-oxide-reduction #carbon-fixation #sustainable-biotechnology #miso-organisms
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