"Taking as few as 3,000 steps per day seems to stave off mental decline by around 3 years in people whose brains have begun to show molecular signs of Alzheimer's disease, but who have yet to display any cognitive symptoms, compared with those who stay sedentary. Up to 7,500 steps per day slows the decline by an average of 7 years, but the effect tails off after that."
"Unlike gene editing in non-reproductive cells, editing an embryo means that changes will be passed down to the next generation, a concept riddled with safety risks and ethical quandaries. Biotech founder Cathy Tie (who publicized a romance with He on social media) says that "a majority of Americans are in support of this technology", and that her company will conduct extensive research and safety testing before attempting to create gene-edited babies."
Taking as few as 3,000 steps per day appears to delay mental decline by about three years in people with molecular signs of Alzheimer's but no cognitive symptoms. Increasing activity to around 7,500 steps per day associates with an average seven-year slowing of decline, with diminishing returns beyond that. Accumulating most daily steps in longer walks links to lower cardiovascular disease risk compared with many very short walks, particularly among those who take fewer than 5,000 steps per day. Several US ventures aim to edit human-embryo genomes to prevent disorders, but heritable edits present safety and ethical challenges and many scientists warn commercialization is premature despite some public support.
#physical-activity #alzheimers-disease #cardiovascular-disease #human-embryo-gene-editing #bioethics
Read at Nature
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