"The latest research review, published Friday in The Lancet Obstetrics, Gynecology & Women's Health, looked at 43 studies and concluded that the most rigorous ones, such as those that compare siblings, provide strong evidence that taking the drug commonly known as paracetamol outside of the U.S. does not cause autism, ADHD or intellectual disabilities. It's safe to use in pregnancy, said lead author Dr. Asma Khalil. It remains the first line of treatment that we would recommend if the pregnant woman has pain or fever."
"One of the papers cited on its web page, published in BMC Environmental Health last year, analyzed results from 46 previous studies and found that they supported evidence of an association between Tylenol exposure during pregnancy and increased incidence of neurodevelopmental disorders. Researchers noted that the drug is still important for treating pain and fever during pregnancy, but said steps should be taken to limit its use. Some health experts have raised concerns about that"
A comprehensive analysis of 43 studies found that the most rigorous designs, including sibling-comparison analyses, show no causal link between prenatal paracetamol (acetaminophen/Tylenol) use and autism, ADHD, or intellectual disabilities. Paracetamol remains the recommended first-line treatment for pain or fever during pregnancy. Some individual studies raised the possibility of a link, but more studies did not find an association, and sibling-comparison analyses produced null results. Other aggregated analyses reported associations and urged limiting use, and some health experts expressed concerns about restricting the drug's use in pregnancy.
Read at www.mercurynews.com
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