""We can cure primary tumors by surgery or radiation. However, when tumor cells start spreading from one place to another, they can get out of control. A lot of times it is devastating and incurable," Liu said."
""Prior studies have increasingly noted a subset of circulating cells that don't fit neatly into traditional definitions of tumor cells or immune cells. These 'dual-positive' cells, or DPcells, display both epithelial tumor markers and immune system markers, suggesting a hybrid or poorly understood role.""
""In the study, investigators analyzed blood samples from 340 patients with advanced breast cancer and found that DPcells are far from irrelevant. Patients with detectable DPcells had significantly worse overall survival than those without them.""
Research reveals that circulating tumor cells (CTCs) play a crucial role in breast cancer progression. These cells can break away from primary tumors and spread through the bloodstream, leading to new tumors. A subset known as dual-positive cells (DPcells) has been identified, which exhibit both tumor and immune markers. Patients with detectable DPcells experience worse survival rates compared to those without, highlighting their clinical significance beyond traditional CTC counts.
Read at News Center
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