"According to the patent, a specific crystalline form of the drug known as polymorph C may be more effective than other versions because it is absorbed more efficiently by the body. The patent also notes that laboratory studies showed the drug reduced tumor growth and helped mice with brain tumors live longer, prompting early clinical trials to test whether the treatment is safe and effective in humans."
"Mebendazole has been used safely for more than four decades to treat parasitic worm infections in humans, but researchers have increasingly investigated whether the drug could also help fight certain cancers, including aggressive brain tumors. The patent itself focuses on how the long-standing anti-parasitic medication might be repurposed as a cancer therapy, particularly for tumors that are difficult to treat with conventional drugs."
"The outrage follows a declassified 1951 CIA report circulated online describing Soviet research that found similarities between parasitic worms and cancer cells and suggested some anti-parasitic drugs could disrupt tumor growth."
Johns Hopkins University patented a potential cancer treatment using mebendazole, an antiparasitic drug safely used for over 40 years. The patent identifies polymorph C, a specific crystalline form of mebendazole, as potentially more effective for cancer treatment due to superior body absorption. Laboratory studies demonstrated the drug reduced tumor growth and extended survival in mice with brain tumors, leading to early clinical trials in humans. The patent filing has generated online controversy, with some claiming the discovery was suppressed by the pharmaceutical industry. Declassified CIA documents from 1951 revealed Soviet research suggesting similarities between parasitic worms and cancer cells, proposing that antiparasitic drugs could disrupt tumor growth.
Read at Mail Online
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