A global study analyzed cancer-causing genes in tumor samples from nearly 500 domestic cats to identify commonly mutated genes. The strongest overlap involved FBXW7, a tumor suppressor critical in both people and cats, which was frequently altered in feline mammary tumors. FBXW7 mutations also correlate with worse outcomes in human breast cancer. Researchers published the findings in Science and reported hope for developing cat treatments while using cat cancers to better understand human cancer and potentially create human therapies. Cats share more genetic code with humans than dogs, cows, or mice, and shared indoor environments can expose both to similar carcinogens.
Read at The Washington Post
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