The Evolution of Brain Stimulation Therapy
Briefly

Even though the origins were based on theories that we now know are not exactly right, it turns out the serendipitous discovery that inducing seizures could be powerfully antidepressant has really transformed how we treat people with severe depression, especially those who were at significant risk of suicide.
Electroconvulsive therapy, known as ECT, has long been mischaracterized in pop culture, but in truth, this is a safe and effective treatment that has provided a road to recovery for many people with hard-to-treat depression.
Read at National Institute of Mental Health (NIMH)
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